| The effect of an extract of Cimicifuga, Remifemin on the proliferation of mamma carcinoma cells in vitro | An E2 concentration of 10-4M caused a significant inhibition of the proliferation rate, Remifemin showed no growth, stimulating effects. Doses including and above 2.5 ug/ml caused a significant inhibition of the proliferation. | Nesselhut T; Schellhase, C; Dietrich, R; Kuhn, W. Archives of Gynaecology and Obstertrics 254 (1993) : 817-818 |
| Clinical and endocrinological examinations concerning therapy of climacteric symptoms following hysterectomy with remaining ovaries. Conjugated oestrogens Vs Remfiemin | In all therapeutic groups decline in the modified menopausal index.- | Lehmann-Wilenbrock, E & Reidel, H.H. Zent, bl. Gynakol. 110 (1998) : 611-618 |
| Menopausal complaints - Change over of a hormone treatment to a herbal gynaecological remedy practicable? |
- Under Remifemin a significant reduction of menopausal
index after 12 weeks was observed (p<0.001). - 56% of the patients under Remifemin therapy required no longer hormone injections - 82% of the patients reported success of Remifemin as good or very good |
Pethö, A Arztl. Praxis 38 (1987) 47: 1551-1553 |
| Phytopharmacon influences astrohpic vaginal epithelium: Remifemin vs oestrogenic substances | Remifemin patients showed the most pronounced reduction, difference of the mean oestrogen or placebo group is highly significant at all 3 control times (p<0.001). The average number of hot flushes per day in the Remifemin group was reduced at 86% at week 12, in the oestrogen group there was a reduction of 38%, in the placebo group of 39%
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Stoll, W Therapeutikum (1987) 1 : 23-31 |
| Phytopharmacon influences atrohpic vaginal epithelium: Remifemin vs oestrogenic substances | Somatic findings: increase of proliferation indices of vaginal epithelium, under Remifemin and conjugated oestrogens as early as 4 weeks after beginning, finally reaching a score at 12 weeks. No changes under Diazepan- Neurovegetative and physical findings : good influence on Menopausal symptoms in all 3 therapy groups, significant reduction of SDS index and modified menopausal index- Clinical global impressions : comparatively good with all 3 therapy forms. | Warnecke, G Med. Welt (1985) : 871-874 |
